ABI2 Antikörper (N-Term)

Produktnummer ABIN2788799

Produktdetails anti-ABI2 Antikörper

Target: ABI2 (Abl-Interactor 2 (ABI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ABI2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Andere Bezeichnung: ABI2 (ABI2 Produkte)

Synonyme: ABI-2 antikoerper, ABI2B antikoerper, AIP-1 antikoerper, AblBP3 antikoerper, SSH3BP2 antikoerper, argBPIA antikoerper, argBPIB antikoerper, 8430425M24Rik antikoerper, AI839867 antikoerper, C130078H13 antikoerper, abl interactor 2 antikoerper, abl-interactor 2 antikoerper, ABI2 antikoerper, abi2 antikoerper, Abi2 antikoerper

Hintergrund: ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Alias Symbols: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Protein Interaction Partner: CCDC36, MRFAP1L1, EGLN3, IFT20, PRAM1, CCDC102B, ARMC7, GCC1, MRPL44, VARS2, KIAA1217, CCHCR1, PRR16, BLOC1S6, TFIP11, NUP62, TRIM32, EFS, STAM2, ABI2, PPIF, ARHGAP32, HOMER3, HGS, EIF3H, NCK2, WIPF1, VASP, TRIP6, SDCBP, PRKAA2, PRKAA1, PIN1, LMO2, KRT33B
Protein Size: 475

Molekulargewicht: 52 kDa

Gen-ID: 10152

NCBI Accession: NM_005759, NP_005750

UniProt: Q9NYB9