ABI2 Antikörper (N-Term)
Kurzübersicht für ABI2 Antikörper (N-Term) (ABIN2788799)
Target
Alle ABI2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ABI2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 475 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ABI2 (Abl-Interactor 2 (ABI2))
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Andere Bezeichnung
- ABI2
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Hintergrund
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ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Alias Symbols: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Protein Interaction Partner: CCDC36, MRFAP1L1, EGLN3, IFT20, PRAM1, CCDC102B, ARMC7, GCC1, MRPL44, VARS2, KIAA1217, CCHCR1, PRR16, BLOC1S6, TFIP11, NUP62, TRIM32, EFS, STAM2, ABI2, PPIF, ARHGAP32, HOMER3, HGS, EIF3H, NCK2, WIPF1, VASP, TRIP6, SDCBP, PRKAA2, PRKAA1, PIN1, LMO2, KRT33B
Protein Size: 475 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 10152
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NCBI Accession
- NM_005759, NP_005750
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UniProt
- Q9NYB9
Target
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