CysLTR1 Antikörper (C-Term)

Produktnummer ABIN2788780

Produktdetails anti-CysLTR1 Antikörper

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Bindungsspezifität: C-Term

Reaktivität: Human, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CysLTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IIPFVIIIVC YTMIILTLLK KSMKKNLSSH KKAIGMIMVV TAAFLVSFMP

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CYSLTR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 337 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Andere Bezeichnung: CYSLTR1 (CYSLTR1 Produkte)

Hintergrund: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Alias Symbols: CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
Protein Interaction Partner: CYSLTR2,
Protein Size: 337

Molekulargewicht: 37 kDa

Gen-ID: 10800

NCBI Accession: NM_006639, NP_006630

UniProt: Q9Y271