NQO1 Antikörper (C-Term)

Produktnummer ABIN2788701

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NQO1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Hund, Kaninchen und Rind (Kuh).

Kurzübersicht für NQO1 Antikörper (C-Term) (ABIN2788701)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reaktivität: Human, Ratte, Hund, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NQO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NQO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Rabbit: 91%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NQO1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NQO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 274 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Andere Bezeichnung: NQO1

Hintergrund: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: UBC, FOS, NEDD8, SUMO1, NFE2L2, PARP1, BAG3, ITGA4, FN1, RPS10P5, POLDIP3, YTHDF1, RPS19, LAMB1, TP53, STUB1, ING1, DNAJB1, HSPA1A, NQO1, HSPA4,
Protein Size: 274

Molekulargewicht: 31 kDa

Gen-ID: 1728

NCBI Accession: NM_000903, NP_000894

UniProt: P15559