RAG2 Antikörper (C-Term)
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- Target Alle RAG2 Antikörper anzeigen
- RAG2 (Recombination Activating Gene 2 (RAG2))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAG2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HLSAGSNKYY CNEHVEIARA LHTPQRVLPL KKPPMKSLRK KGSGKILTPA
- Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RAG2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product RAG2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 527 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAG2 (Recombination Activating Gene 2 (RAG2))
- Andere Bezeichnung
- RAG2 (RAG2 Produkte)
- Synonyme
- RAG-2 antikoerper, Rag-2 antikoerper, rag-2 antikoerper, zgc:136743 antikoerper, recombination activating 2 antikoerper, recombination activating gene 2 antikoerper, recombination activating gene 2 S homeolog antikoerper, RAG2 antikoerper, Rag2 antikoerper, rag2 antikoerper, rag2.S antikoerper
- Hintergrund
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This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4.
Alias Symbols: RAG-2
Protein Interaction Partner: RAG1, VPRBP, DDB1, UBC, SKP2, IPO5, KPNA1, tax,
Protein Size: 527 - Molekulargewicht
- 59 kDa
- Gen-ID
- 5897
- NCBI Accession
- NM_000536, NP_000527
- UniProt
- P55895
- Pathways
- Chromatin Binding, Production of Molecular Mediator of Immune Response
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