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RAG2 Antikörper (C-Term)

Der Kaninchen-Polyklonal Anti-RAG2-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von RAG2 in Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. }
Produktnummer ABIN2788687
534,11 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 6 bis 8 Werktagen

Kurzübersicht für RAG2 Antikörper (C-Term) (ABIN2788687)

Target

Alle RAG2 Antikörper anzeigen
RAG2 (Recombination Activating Gene 2 (RAG2))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt

  • 40
  • 8
Kaninchen

Klonalität

  • 42
  • 6
Polyklonal

Konjugat

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RAG2 Antikörper ist unkonjugiert

Applikation

  • 21
  • 14
  • 13
  • 13
  • 7
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    HLSAGSNKYY CNEHVEIARA LHTPQRVLPL KKPPMKSLRK KGSGKILTPA

    Homologie

    Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against RAG2. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 527 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    RAG2 (Recombination Activating Gene 2 (RAG2))

    Andere Bezeichnung

    RAG2

    Hintergrund

    This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4.
    Alias Symbols: RAG-2
    Protein Interaction Partner: RAG1, VPRBP, DDB1, UBC, SKP2, IPO5, KPNA1, tax,
    Protein Size: 527

    Molekulargewicht

    59 kDa

    Gen-ID

    5897

    NCBI Accession

    NM_000536, NP_000527

    UniProt

    P55895

    Pathways

    Chromatin Binding, Production of Molecular Mediator of Immune Response
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