SORD Antikörper (N-Term)

Produktnummer ABIN2788686

Produktdetails anti-SORD Antikörper

Target: SORD (Sorbitol Dehydrogenase (SORD))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Kaninchen, Schwein, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SORD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SORD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 357 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD (SORD Produkte)

Synonyme: SORD1 antikoerper, Sdh-1 antikoerper, Sdh1 antikoerper, Sodh-1 antikoerper, SDH antikoerper, sord antikoerper, MGC83437 antikoerper, BmSDH antikoerper, PSPTO0363 antikoerper, SODH-1 antikoerper, RATSDHE1 antikoerper, SDH2 antikoerper, Sdh antikoerper, Sdhe1 antikoerper, TDH antikoerper, 4733401P19Rik antikoerper, AI836084 antikoerper, CGI-97 antikoerper, SDS antikoerper, zgc:63674 antikoerper, sorbitol dehydrogenase antikoerper, sorbitol dehydrogenase L homeolog antikoerper, Sorbitol dehydrogenase antikoerper, serine dehydratase antikoerper, SBDS ribosome maturation factor antikoerper, SORD antikoerper, Sord antikoerper, sord.L antikoerper, sord antikoerper, Sdh antikoerper, LOC733025 antikoerper, polS antikoerper, RS_RS10765 antikoerper, sdh antikoerper, smoS antikoerper, Rsph17029_1731 antikoerper, Srd antikoerper, RSKD131_1411 antikoerper, SDS antikoerper, Sds antikoerper, Sbds antikoerper

Hintergrund: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Alias Symbols: SORD1
Protein Interaction Partner: SORD, SUMO2, UBC, C12orf10, BCCIP, NAGK, CHORDC1, ACOT7, DDX39A, GDA, THOP1, TCEA1, TALDO1, SMS, PLS3, PGD, NME1, LDHA, FDPS, RELA, C16orf13, FLAD1, PIEZO1, TPM1, RANGAP1, RAD23A, PFDN4, GCLM, ETFA, AKR1B1, NUDCD2, LOC440434, TIPRL, SHBG,
Protein Size: 357

Molekulargewicht: 38 kDa

Gen-ID: 6652

NCBI Accession: NM_003104, NP_003095

UniProt: Q00796