SORD Antikörper (N-Term)

Produktnummer ABIN2788686

Der Kaninchen Polyklonal anti-SORD Antikörper (ABIN2788686) detektiert spezifisch SORD in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Kaninchen, Schwein, Meerschweinchen und Pferd.

Kurzübersicht für SORD Antikörper (N-Term) (ABIN2788686)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Kaninchen, Schwein, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SORD Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SORD Antibody - N-terminal region

Sequenz: ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SORD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SORD

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61128-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD

Hintergrund:

Background Information: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Gene Name: Sorbitol dehydrogenase

Alternative Symbols: RDH, SDH, XDH, SORD1, SORDD, HEL-S-95n

Protein Name: Sorbitol dehydrogenase

Molekulargewicht: 38kDa

Gen-ID: 6652

NCBI Accession: NP_003095

UniProt: Q00796