TPR Antikörper (C-Term)

Produktnummer ABIN2788674

Produktdetails anti-TPR Antikörper

Target: TPR (Nucleoprotein TPR (TPR))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Kaninchen, Rind (Kuh), Ratte, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SSEAGLEIDS QQEEEPVQAS DESDLPSTSQ DPPSSSSVDT SSSQPKPFRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TPR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TPR

Target: TPR (Nucleoprotein TPR (TPR))

Andere Bezeichnung: TPR (TPR Produkte)

Synonyme: AtTPR antikoerper, TRANSLOCATED PROMOTER REGION antikoerper, YUP8H12R.12 antikoerper, YUP8H12R_12 antikoerper, nuclear pore anchor antikoerper, 2610029M07Rik antikoerper, C77892 antikoerper, translocated promoter region, nuclear basket protein antikoerper, nuclear pore anchor antikoerper, TPR antikoerper, NUA antikoerper, Tpr antikoerper

Hintergrund: This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
Alias Symbols: -
Protein Interaction Partner: STAU1, UBC, LGR4, MDM2, MAD1L1, EED, NPM1, LMNA, HDAC9, ITGA4, FN1, CBX7, BUD31, TAF15, TOP1, SNRPD1, SNRPA1, SRSF5, SFPQ, S100A9, RPL37A, RPL18A, RPL6, RBM4, RAN, PRKDC, NHP2L1, SEPT2, IK, HRAS, HNRNPU, HNRNPA2B1, EEF1D, EEF1B2, DDX3X, DDX1, DDB1, CIRBP,
Protein Size: 2363

Molekulargewicht: 267 kDa

Gen-ID: 7175

NCBI Accession: NM_003292, NP_003283

UniProt: P12270