Topoisomerase I Antikörper (N-Term)
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- Target Alle Topoisomerase I (TOP1) Antikörper anzeigen
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Topoisomerase I Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TOP1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product TOP1 Primärantikörper
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anti-Topoisomerase (DNA) I (TOP1) (AA 692-765) antibody
TOP1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1A1 unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 Reaktivität: Human WB, ELISA, IHC, IP, FACS Wirt: Kaninchen Monoclonal 6D8 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (N-Term) antibodyTOP1 Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 1291CT875-142-166 unconjugated
anti-Topoisomerase (DNA) I (TOP1) (Internal Region) antibodyTOP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 1-100) antibodyTOP1 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 2-31), (N-Term) antibodyTOP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB34034 unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 358-501) antibodyTOP1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 Reaktivität: Human, Ratte WB, FACS Wirt: Maus Monoclonal 1C6 unconjugated
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 765 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- Andere Bezeichnung
- TOP1 (TOP1 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Alias Symbols: TOPI
Protein Interaction Partner: SUMO2, SUMO3, MDM2, UBC, SUMO1, ERG, RNF2, EED, SHFM1, CDK14, TARDBP, CDK2, HDAC9, EIF2AK2, PARP1, WHSC1, VCAM1, ITGA4, IL7R, VCP, PA2G4, NKX3-1, ESR1, RBM39, APP, UTP20, NCSTN, SUPT16H, RBM14, SF3B6, SRSF11, TPR, SNRPD1, S100A9, RPS14, HNRNPM, IK, HNRNPC
Protein Size: 765 - Molekulargewicht
- 91 kDa
- Gen-ID
- 7150
- NCBI Accession
- NM_003286, NP_003277
- UniProt
- P11387
- Pathways
- Caspase Kaskade in der Apoptose, Stem Cell Maintenance
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