Calpain 3 Antikörper (Middle Region)

Produktnummer ABIN2788628

Der Kaninchen Polyklonal anti-Calpain 3 Antikörper wird verwendet zum Nachweis von Calpain 3 in Proben von Human, Maus, Ratte, Rind (Kuh), Schaf, Hund und Pferd. Er wurde validiert für WB.

Kurzübersicht für Calpain 3 Antikörper (Middle Region) (ABIN2788628)

Target: Calpain 3 (CAPN3)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Calpain 3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SPQPQPGSSD QESEEQQQFR NIFKQIAGDD MEICADELKK VLNTVVNKHK

Homologie: Cow: 75%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against CAPN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 309 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Calpain 3

Target: Calpain 3 (CAPN3)

Andere Bezeichnung: CAPN3

Hintergrund: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Alias Symbols: CANP3, CANPL3, LGMD2, LGMD2A, MGC10767, MGC11121, MGC14344, MGC4403, nCL-1, p94
Protein Interaction Partner: WDYHV1, OSGIN1, NECAB2, DYSF, TTN, YWHAQ, CAPN3, FLNC,
Protein Size: 309

Molekulargewicht: 35 kDa

Gen-ID: 825

NCBI Accession: NM_173088, NP_775111

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development