Calpain 3 Antikörper (C-Term)

Produktnummer ABIN2788627

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Calpain 3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Meerschweinchen und Kaninchen.

Kurzübersicht für Calpain 3 Antikörper (C-Term) (ABIN2788627)

Target: Calpain 3 (CAPN3)

Reaktivität: Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Calpain 3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CAPN3 Antibody - C-terminal region

Sequenz: DRANSNKELG VDQESEEGKG KTSPDKQKQS PQPQPGSSDQ ESEEQQQFRN

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 85%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CAPN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60946-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Calpain 3

Target: Calpain 3 (CAPN3)

Andere Bezeichnung: CAPN3

Hintergrund:

Background Information: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Gene Name: Calpain 3, (p94)

Alternative Symbols: p94, CANP3, LGMD2, nCL-1, CANPL3, LGMD2A, LGMDD4, LGMDR1

Protein Name: Calpain-3

Molekulargewicht: 93kDa

Gen-ID: 825

NCBI Accession: NP_077320

UniProt: P20807

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development