Calpain 3 Antikörper (C-Term)
Kurzübersicht für Calpain 3 Antikörper (C-Term) (ABIN2788627)
Target
Alle Calpain 3 (CAPN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- C-Term
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                                            Sequenz
- DRANSNKELG VDQESEEGKG KTSPDKQKQS PQPQPGSSDQ ESEEQQQFRN
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                                            Homologie
- Cow: 79%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 85%, Sheep: 86%
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                                            Produktmerkmale
- This is a rabbit polyclonal antibody against CAPN3. It was validated on Western Blot.
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                                            Aufreinigung
- Affinity Purified
 
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                                            Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            Kommentare
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                        Antigen size: 815 AA 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Konzentration
- Lot specific
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                                            Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freeze-thaw cycles.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - Calpain 3 (CAPN3)
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                                            Andere Bezeichnung
- CAPN3
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                                            Hintergrund
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                        Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
 Alias Symbols: CANP3, CANPL3, LGMD2, LGMD2A, MGC10767, MGC11121, MGC14344, MGC4403, nCL-1, p94
 Protein Interaction Partner: WDYHV1, OSGIN1, NECAB2, DYSF, TTN, YWHAQ, CAPN3, FLNC,
 Protein Size: 815
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                                            Molekulargewicht
- 93 kDa
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                                            Gen-ID
- 825
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                                            NCBI Accession
- NM_024344, NP_077320
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                                            Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
 Target
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