PANK2 Antikörper (Middle Region)

Produktnummer ABIN2788602

Dieses Anti-PANK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PANK2 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Schaf.

Kurzübersicht für PANK2 Antikörper (Middle Region) (ABIN2788602)

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PANK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PANK2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FGLPGWAVAS SFGNMMSKEK REAVSKEDLA RATLITITNN IGSIARMCAL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PANK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of HUMAN PANK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PANK2

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Andere Bezeichnung: PANK2

Hintergrund: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
Protein Interaction Partner: UBC, DHX36, QRICH2, LXN, YWHAQ, VDAC1, RASGRF2,
Protein Size: 460

Molekulargewicht: 50 kDa

Gen-ID: 80025

Pathways: Ribonucleoside Biosynthetic Process