AKR1D1 Antikörper (Middle Region)

Produktnummer ABIN2788589

Produktdetails anti-AKR1D1 Antikörper

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL

Homologie: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against AKR1D1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 326 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKR1D1

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Andere Bezeichnung: AKR1D1 (AKR1D1 Produkte)

Synonyme: 3o5bred antikoerper, CBAS2 antikoerper, SRD5B1 antikoerper, 3-oxo-5-beta-steroid 4-dehydrogenase-like antikoerper, aldo-keto reductase family 1 member D1 antikoerper, aldo-keto reductase family 1, member D1 antikoerper, aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) antikoerper, LOC491379 antikoerper, AKR1D1 antikoerper, Akr1d1 antikoerper

Hintergrund: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Alias Symbols: 3o5bred, CBAS2, SRD5B1
Protein Size: 326

Molekulargewicht: 37 kDa

Gen-ID: 6718

NCBI Accession: NM_005989, NP_005980

UniProt: P51857

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process