AKR1D1 Antikörper (Middle Region)
Kurzübersicht für AKR1D1 Antikörper (Middle Region) (ABIN2788589)
Target
Alle AKR1D1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL
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Homologie
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 100%, Rat: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AKR1D1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 326 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
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Andere Bezeichnung
- AKR1D1
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Hintergrund
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The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Alias Symbols: 3o5bred, CBAS2, SRD5B1
Protein Size: 326 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 6718
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NCBI Accession
- NM_005989, NP_005980
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UniProt
- P51857
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Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
Target
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