IL-27 Antikörper (C-Term)

Produktnummer ABIN2788559

Der Kaninchen Polyklonal anti-IL-27 Antikörper (ABIN2788559) detektiert spezifisch IL-27 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-27 Antikörper (C-Term) (ABIN2788559)

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-27 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IL27 Antibody - C-terminal region

Sequenz: AQVSWPQLLS TYRLLHSLEL VLSRAVRELL LLSKAGHSVW PLGFPTLSPQ

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL27. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IL27

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60748-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-27

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Andere Bezeichnung: IL27

Hintergrund:

Targeted Subunit: alpha

Background Information: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene Name: Interleukin 27

Alternative Symbols: p28, IL30, IL-27, IL27A, IL-27A, IL27p28

Protein Name: Interleukin-27 subunit alpha

Molekulargewicht: 27kDa

Gen-ID: 246778

NCBI Accession: NP_663634

UniProt: Q8NEV9