IL-27 Antikörper (C-Term)

Produktnummer ABIN2788559

Dieses Anti-IL-27-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL-27 in WB. Geeignet für Human.

Kurzübersicht für IL-27 Antikörper (C-Term) (ABIN2788559)

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-27 Antikörper

Bindungsspezifität: C-Term

Sequenz: AQVSWPQLLS TYRLLHSLEL VLSRAVRELL LLSKAGHSVW PLGFPTLSPQ

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL27. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IL27

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 243 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-27

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Andere Bezeichnung: IL27

Hintergrund: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Alias Symbols: IL-27, IL-27A, IL27p28, IL30, MGC71873, p28, IL27A
Protein Interaction Partner: IL27RA,
Protein Size: 243

Molekulargewicht: 27 kDa

Gen-ID: 246778

NCBI Accession: NM_145659, NP_663634

UniProt: Q8NEV9