MARCKS Antikörper (C-Term)
Kurzübersicht für MARCKS Antikörper (C-Term) (ABIN2788405)
Target
Alle MARCKS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA
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Homologie
- Cow: 86%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 77%, Yeast: 80%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MARCKS. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 332 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Andere Bezeichnung
- MARCKS
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Hintergrund
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The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
Protein Interaction Partner: UBC, TUBGCP3, UBQLN2, RPA2, PRKACA, PARK2, PKN1, PRKCB, HCVgp1, ATF2, PRKCZ, HSP90AA1, HNRNPU, DFFB, DBN1, SPP1, CDK4, CDK2, CDK1, CCNE1, ELAVL1, EBNA-LP, Mapk13, TOB1, PRKCA, NMT1, CTSB, CALM3, CALM2,
Protein Size: 332 -
Molekulargewicht
- 31 kDa
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Gen-ID
- 4082
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NCBI Accession
- NM_002356, NP_002347
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UniProt
- P29966
Target
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