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MARCKS Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-MARCKS-Antikörper wurde für WB und IHC validiert. Er ist geeignet, MARCKS in Proben von Human, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Schwein und Saccharomyces cerevisiae zu detektieren.
Produktnummer ABIN2788405

Kurzübersicht für MARCKS Antikörper (C-Term) (ABIN2788405)

Target

Alle MARCKS Antikörper anzeigen
MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reaktivität

  • 98
  • 67
  • 65
  • 8
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
Human, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Schwein, Saccharomyces cerevisiae

Wirt

  • 111
  • 5
  • 1
Kaninchen

Klonalität

  • 112
  • 5
Polyklonal

Konjugat

  • 63
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser MARCKS Antikörper ist unkonjugiert

Applikation

  • 74
  • 37
  • 27
  • 27
  • 21
  • 18
  • 11
  • 7
  • 7
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 28
    • 20
    • 19
    • 10
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA

    Homologie

    Cow: 86%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 77%, Yeast: 80%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against MARCKS. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 332 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

    Andere Bezeichnung

    MARCKS

    Hintergrund

    The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
    Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
    Protein Interaction Partner: UBC, TUBGCP3, UBQLN2, RPA2, PRKACA, PARK2, PKN1, PRKCB, HCVgp1, ATF2, PRKCZ, HSP90AA1, HNRNPU, DFFB, DBN1, SPP1, CDK4, CDK2, CDK1, CCNE1, ELAVL1, EBNA-LP, Mapk13, TOB1, PRKCA, NMT1, CTSB, CALM3, CALM2,
    Protein Size: 332

    Molekulargewicht

    31 kDa

    Gen-ID

    4082

    NCBI Accession

    NM_002356, NP_002347

    UniProt

    P29966
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