Cathepsin E Antikörper (N-Term)

Produktnummer ABIN2788342

Produktdetails anti-Cathepsin E Antikörper

Target: Cathepsin E (CTSE)

Bindungsspezifität: N-Term

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLKKKLRARS QLSEFWKSHN LDMIQFTESC SMDQSAKEPL INYLDMEYFG

Homologie: Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CTSE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cathepsin E

Target: Cathepsin E (CTSE)

Andere Bezeichnung: CTSE (CTSE Produkte)

Hintergrund: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Alias Symbols: CATE
Protein Interaction Partner: EMG1, INS, BAG6, EDN3, CTSE, A2M,
Protein Size: 363

Molekulargewicht: 40 kDa

Gen-ID: 1510

NCBI Accession: NM_148964, NP_683865

UniProt: P14091