CTSC Antikörper (N-Term)

Produktnummer ABIN2788337

Der Kaninchen Polyklonal anti-CTSC Antikörper wird verwendet zum Nachweis von CTSC in Proben von Human, Ratte, Schwein und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für CTSC Antikörper (N-Term) (ABIN2788337)

Target: CTSC (Cathepsin C (CTSC))

Reaktivität: Human, Ratte, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CTSC Antikörper

Bindungsspezifität: N-Term

Sequenz: VNIAHLKNSQ EKYSNRLYKY DHNFVKAINA IQKSWTATTY MEYETLTLGD

Homologie: Human: 100%, Pig: 79%, Rabbit: 90%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTSC

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CTSC

Target: CTSC (Cathepsin C (CTSC))

Andere Bezeichnung: CTSC

Hintergrund: CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
Protein Size: 463

Molekulargewicht: 50 kDa

Gen-ID: 1075

UniProt: P53634