CTSC Antikörper (N-Term)

Produktnummer ABIN2788337

Produktdetails anti-CTSC Antikörper

Target: CTSC (Cathepsin C (CTSC))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VNIAHLKNSQ EKYSNRLYKY DHNFVKAINA IQKSWTATTY MEYETLTLGD

Homologie: Human: 100%, Pig: 79%, Rabbit: 90%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTSC

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CTSC

Target: CTSC (Cathepsin C (CTSC))

Andere Bezeichnung: CTSC (CTSC Produkte)

Synonyme: CPPI antikoerper, DPP-I antikoerper, DPP1 antikoerper, DPPI antikoerper, HMS antikoerper, JP antikoerper, JPD antikoerper, PALS antikoerper, PDON1 antikoerper, PLS antikoerper, MGC69126 antikoerper, MGC107782 antikoerper, AI047818 antikoerper, CATC antikoerper, cb912 antikoerper, ik:tdsubc_1h2 antikoerper, sb:cb146 antikoerper, wu:fb34g12 antikoerper, wu:fj58d01 antikoerper, cathepsin C antikoerper, cathepsin C L homeolog antikoerper, cathepsin CPC1 antikoerper, CTSC antikoerper, ctsc.L antikoerper, ctsc antikoerper, TP03_0357 antikoerper, CMU_003360 antikoerper, CPC1 antikoerper, NAEGRDRAFT_80477 antikoerper, NAEGRDRAFT_37577 antikoerper, Ctsc antikoerper, Smp_183330 antikoerper

Hintergrund: CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
Protein Size: 463

Molekulargewicht: 50 kDa

Gen-ID: 1075

UniProt: P53634