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Factor VIII Antikörper (C-Term)

F8 Reaktivität: Human, Hund, Kaninchen, Rind (Kuh), Schaf, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788318
  • Target Alle Factor VIII (F8) Antikörper anzeigen
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Bindungsspezifität
    • 15
    • 15
    • 15
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 94
    • 59
    • 30
    • 16
    • 9
    • 3
    • 1
    • 1
    • 1
    Human, Hund, Kaninchen, Rind (Kuh), Schaf, Pferd
    Wirt
    • 87
    • 21
    • 4
    • 2
    Kaninchen
    Klonalität
    • 94
    • 20
    Polyklonal
    Konjugat
    • 49
    • 15
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Factor VIII Antikörper ist unkonjugiert
    Applikation
    • 54
    • 42
    • 39
    • 39
    • 24
    • 11
    • 10
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IMVTFRNQAS RPYSFYSSLI SYEEDQRQGA EPRKNFVKPN ETKTYFWKVQ
    Homologie
    Cow: 86%, Dog: 77%, Horse: 93%, Human: 100%, Rabbit: 86%, Sheep: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against F8. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human F8
    Top Product
    Discover our top product F8 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 2351 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Andere Bezeichnung
    F8 (F8 Produkte)
    Synonyme
    fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper
    Hintergrund
    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
    Alias Symbols: AHF, DXS1253E, F8B, F8C, FVIII, HEMA
    Protein Interaction Partner: UBQLN1, GGA1, MCFD2, PHYH, LMAN1, F9, F10, VWF, F2, PROS1, PROC, HSPA5, CANX, CALR, ASGR2, LRP1,
    Protein Size: 2351
    Molekulargewicht
    79 kDa
    Gen-ID
    2157
    NCBI Accession
    NM_000132, NP_000123
    UniProt
    P00451
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