Factor VII Antikörper (C-Term)

Produktnummer ABIN2788316

Der Kaninchen Polyklonal anti-Factor VII Antikörper (ABIN2788316) detektiert spezifisch Factor VII in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Kaninchen und Hund.

Kurzübersicht für Factor VII Antikörper (C-Term) (ABIN2788316)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reaktivität: Human, Maus, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Factor VII Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: F7 Antibody - C-terminal region

Sequenz: AAHCFDKIKN WRNLIAVLGE HDLSEHDGDE QSRRVAQVII PSTYVPGTTN

Homologie: Dog: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against F7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human F7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60038-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: F7

Hintergrund:

Background Information: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.

Gene Name: Coagulation factor VII (serum prothrombin conversion accelerator)

Alternative Symbols: SPCA

Protein Name: Coagulation factor VII

Molekulargewicht: 28kDa

Gen-ID: 2155

NCBI Accession: NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling