F2RL1 Antikörper (C-Term)
Kurzübersicht für F2RL1 Antikörper (C-Term) (ABIN2788314)
Target
Alle F2RL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- C-Term
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                                            Sequenz
- VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
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                                            Homologie
- Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%
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                                            Produktmerkmale
- This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
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                                            Aufreinigung
- Affinity Purified
 
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                                            Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            Kommentare
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                        Antigen size: 397 AA 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Konzentration
- Lot specific
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                                            Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freeze-thaw cycles.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - 
                                            : "Toward drugs for protease-activated receptor 2 (PAR2)."    in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013)         (PubMed).        
 
 
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                                            : "Toward drugs for protease-activated receptor 2 (PAR2)."    in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013)         (PubMed).        
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    - F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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                                            Andere Bezeichnung
- F2RL1
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                                            Hintergrund
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                        Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence. 
 Alias Symbols: GPR11, PAR2
 Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
 Protein Size: 397
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                                            Molekulargewicht
- 44 kDa
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                                            Gen-ID
- 2150
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                                            NCBI Accession
- NM_005242, NP_005233
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                                            UniProt
- P55085
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                                            Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom
 Target
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