ADRA2C Antikörper (C-Term)

Produktnummer ABIN2788285

Der Kaninchen Polyklonal anti-ADRA2C Antikörper (ABIN2788285) detektiert spezifisch ADRA2C in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Schwein.

Kurzübersicht für ADRA2C Antikörper (C-Term) (ABIN2788285)

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADRA2C Antikörper

Bindungsspezifität: C-Term

Sequenz: RAGAEGGAGG ADGQGAGPGA AESGALTASR EWGGERGRPL CLPPSARGCF

Homologie: Human: 100%, Pig: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ADRA2C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Andere Bezeichnung: ADRA2C

Hintergrund: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Alias Symbols: ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR
Protein Size: 374

Molekulargewicht: 41 kDa

Gen-ID: 152

NCBI Accession: NM_000683, NP_000674

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process