ADRA1B Antikörper (N-Term)

Produktnummer ABIN2788282

Der Kaninchen Polyklonal Anti-ADRA1B-Antikörper wurde für WB validiert. Er ist geeignet, ADRA1B in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd zu detektieren.

Kurzübersicht für ADRA1B Antikörper (N-Term) (ABIN2788282)

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADRA1B Antikörper

Bindungsspezifität: N-Term

Sequenz: VWVLSTVISI GPLLGWKEPA PNDDKECGVT EEPFYALFSS LGSFYIPLAV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ADRA1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADRA1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Andere Bezeichnung: ADRA1B

Hintergrund: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene
Alias Symbols: ADRA1, ALPHA1BAR
Protein Interaction Partner: ALB, AP2M1, GNAQ, STAT1, SAG, PRKCA, NOS1, GNA11, EZR, ADRA1A, FLNC,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 147

NCBI Accession: NM_000679, NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process