ADRA1B Antikörper (N-Term)

Produktnummer ABIN2788282

Der Kaninchen Polyklonal anti-ADRA1B Antikörper wird verwendet zum Nachweis von ADRA1B in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für ADRA1B Antikörper (N-Term) (ABIN2788282)

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADRA1B Antikörper

Bindungsspezifität: N-Term

Sequenz: VWVLSTVISI GPLLGWKEPA PNDDKECGVT EEPFYALFSS LGSFYIPLAV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ADRA1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADRA1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Andere Bezeichnung: ADRA1B

Hintergrund: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene
Alias Symbols: ADRA1, ALPHA1BAR
Protein Interaction Partner: ALB, AP2M1, GNAQ, STAT1, SAG, PRKCA, NOS1, GNA11, EZR, ADRA1A, FLNC,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 147

NCBI Accession: NM_000679, NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process