Rho-related GTP-binding protein Antikörper (C-Term)

Produktnummer ABIN2788258

Produktdetails anti-Rho-related GTP-binding protein Antikörper

Target: Rho-related GTP-binding protein (RhO (pan))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rho-related GTP-binding protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RHO. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RHO

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 348 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Rho-related GTP-binding protein

Target: Rho-related GTP-binding protein (RhO (pan))

Andere Bezeichnung: RHO (RhO (pan) Produkte)

Substanzklasse: Chemical

Hintergrund: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Alias Symbols: CSNBAD1, MGC138309, MGC138311, OPN2, RP4
Protein Interaction Partner: DERL1, EDEM1, VCP, UBC, HSPA4, DNAJB2, RHO, PPP2CA, GRK5, GRK6, ARR3, GNGT1, SAG, GRK1, PRKCA, ADRBK1,
Protein Size: 348

Molekulargewicht: 39 kDa

Gen-ID: 6010

NCBI Accession: NM_000539, NP_000530

UniProt: P08100