MAGE-Like 2 Antikörper (N-Term)

Produktnummer ABIN2788252

Der Kaninchen Polyklonal anti-MAGE-Like 2 Antikörper wird verwendet zum Nachweis von MAGE-Like 2 in Proben von Human, Rind (Kuh), Hund, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für MAGE-Like 2 Antikörper (N-Term) (ABIN2788252)

Target: MAGE-Like 2 (MAGEL2)

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGE-Like 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAGE-Like 2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAGEL2 Antibody - N-terminal region

Sequenz: MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP

Homologie: Cow: 83%, Dog: 100%, Human: 100%, Pig: 88%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59891-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Andere Bezeichnung: MAGEL2

Hintergrund:

Background Information: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

Gene Name: MAGE-like 2

Alternative Symbols: PWLS, nM15, NDNL1, SHFYNG

Protein Name: MAGE-like protein 2

Molekulargewicht: 58kDa

Gen-ID: 54551

UniProt: Q9UJ55