MAGE-Like 2 Antikörper (N-Term)
Kurzübersicht für MAGE-Like 2 Antikörper (N-Term) (ABIN2788252)
Target
Alle MAGE-Like 2 (MAGEL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP
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Homologie
- Cow: 83%, Dog: 100%, Human: 100%, Pig: 88%, Rabbit: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 529 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAGE-Like 2 (MAGEL2)
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Andere Bezeichnung
- MAGEL2
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Hintergrund
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Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Alias Symbols: NDNL1, nM15
Protein Interaction Partner: VPS35, VPS26A, USP7, TRIM27, UBC,
Protein Size: 529 -
Molekulargewicht
- 58 kDa
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Gen-ID
- 54551
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NCBI Accession
- NM_019066
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UniProt
- Q9UJ55
Target
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