IGSF8 Antikörper (Middle Region)

Produktnummer ABIN2788247

Dieser Anti-IGSF8 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IGSF8 in WB. Geeignet für Human, Maus, Rind (Kuh), Schwein, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für IGSF8 Antikörper (Middle Region) (ABIN2788247)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reaktivität: Human, Maus, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGSF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IGSF8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 83%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IGSF8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IGSF8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 613 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Andere Bezeichnung: IGSF8

Hintergrund: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Alias Symbols: CD316, CD81P3, EWI2, PGRL, EWI-2, KCT-4, LIR-D1
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, KRTAP10-4, UBC, FBXO6, HIST1H2BK, TUBB6, TUBB7P, VPS35, TUBA8, EIF3L, TUBE1, RPL26L1, YBX2, EIF3K, LSM3, PDCD4, PABPC1, IBTK, RPL36, RPL13A, SF3B3, RPL35, SUPT16H, SRSF8, PRPF8, CCT4, ANP32B, DDX17, SYNCRIP, TUB
Protein Size: 613

Molekulargewicht: 65 kDa

Gen-ID: 93185

NCBI Accession: NM_052868, NP_443100

UniProt: Q969P0