CERKL Antikörper (N-Term)

Produktnummer ABIN2788233

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CERKL in WB. Er zeigt eine Reaktivität gegenüber Human, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Rind (Kuh) und Schwein.

Kurzübersicht für CERKL Antikörper (N-Term) (ABIN2788233)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reaktivität: Human, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERKL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CERKL Antikörper

Bindungsspezifität: N-Term

Sequenz: TLDLINLSED HCDIWFRQFK KILAGFPNRP KSLKILLNPQ SHKKEATQVY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CERKL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 532 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Andere Bezeichnung: CERKL

Hintergrund: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 532

Molekulargewicht: 59 kDa

Gen-ID: 375298

NCBI Accession: NM_201548, NP_963842

UniProt: Q49MI3