CERKL Antikörper (N-Term)

Produktnummer ABIN2788233

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CERKL in WB. Er zeigt eine Reaktivität gegenüber Human, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Rind (Kuh) und Schwein.

Kurzübersicht für CERKL Antikörper (N-Term) (ABIN2788233)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reaktivität: Human, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERKL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CERKL Antikörper

Bindungsspezifität: N-Term

Sequenz: TLDLINLSED HCDIWFRQFK KILAGFPNRP KSLKILLNPQ SHKKEATQVY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CERKL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 532 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Andere Bezeichnung: CERKL

Hintergrund: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 532

Molekulargewicht: 59 kDa

Gen-ID: 375298

NCBI Accession: NM_201548, NP_963842

UniProt: Q49MI3