CERKL Antikörper (C-Term)

Produktnummer ABIN2788232

Dieses Anti-CERKL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CERKL in WB. Geeignet für Human, Maus, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für CERKL Antikörper (C-Term) (ABIN2788232)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reaktivität: Human, Maus, Kaninchen, Pferd, Hund, Meerschweinchen, Ratte, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERKL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CERKL Antikörper

Bindungsspezifität: C-Term

Sequenz: ASVKNQFNFP FVETYTVEEV KVHPRNNTGG YNPEEEEDET ASENCFPWNV

Homologie: Dog: 90%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 81%, Rat: 79%, Yeast: 89%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CERKL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 463 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Andere Bezeichnung: CERKL

Hintergrund: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 463

Molekulargewicht: 51 kDa

Gen-ID: 375298

NCBI Accession: NM_001030313, NP_001025484

UniProt: Q49MI3