GRK1 Antikörper (Middle Region)

Produktnummer ABIN2788207

Der Kaninchen Polyklonal anti-GRK1 Antikörper (ABIN2788207) detektiert spezifisch GRK1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Pferd und Schwein.

Kurzübersicht für GRK1 Antikörper (Middle Region) (ABIN2788207)

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRK1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NKELKHRIIS EPVKYPDKFS QASKDFCEAL LEKDPEKRLG FRDETCDKLR

Homologie: Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against GRK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 563 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Andere Bezeichnung: GRK1

Hintergrund: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
Alias Symbols: GPRK1, RHOK, RK
Protein Interaction Partner: MYC, PDE6D, CAV1, GRK1, RHO, RCVRN, CALM1, SNCG, SNCA, SNCB,
Protein Size: 563

Molekulargewicht: 63 kDa

Gen-ID: 6011

NCBI Accession: NM_002929, NP_002920

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction