ARHGEF2 Antikörper (C-Term)

Produktnummer ABIN2788156

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARHGEF2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für ARHGEF2 Antikörper (C-Term) (ABIN2788156)

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARHGEF2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ARHGEF2 Antibody - C-terminal region

Sequenz: NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGEF2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59669-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Andere Bezeichnung: ARHGEF2

Hintergrund:

Background Information: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Rho/Rac guanine nucleotide exchange factor (GEF) 2

Alternative Symbols: GEF, Lfc, P40, GEFH1, LFP40, GEF-H1, NEDMHM

Protein Name: Rho guanine nucleotide exchange factor 2

Molekulargewicht: 111kDa

Gen-ID: 9181

NCBI Accession: NP_001155855

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling