ARHGEF2 Antikörper (C-Term)

Produktnummer ABIN2788156

Produktdetails anti-ARHGEF2 Antikörper

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGEF2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 986 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Andere Bezeichnung: ARHGEF2 (ARHGEF2 Produkte)

Synonyme: MGC82333 antikoerper, MGC86214 antikoerper, MGC75855 antikoerper, AA408978 antikoerper, GEF antikoerper, GEF-H1 antikoerper, GEFH1 antikoerper, LFP40 antikoerper, Lbcl1 antikoerper, Lfc antikoerper, P40 antikoerper, mKIAA0651 antikoerper, GEF-H1/LFC antikoerper, Rho/Rac guanine nucleotide exchange factor 2 antikoerper, Rho/Rac guanine nucleotide exchange factor 2 S homeolog antikoerper, rho/rac guanine nucleotide exchange factor (GEF) 2 antikoerper, ARHGEF2 antikoerper, arhgef2.S antikoerper, arhgef2 antikoerper, Arhgef2 antikoerper

Hintergrund: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Protein Interaction Partner: RPP25L, UBC, CEP250, RPA3, RPA2, RPA1, PPP6C, FBXO6, ANKRD28, PPP6R1, YWHAB, MMS19, PEX14, VCP, NOTCH1, YWHAZ, MARK2, RHOA, AKT1, USP21, ELAVL1, SUMO1, MARK4, YWHAH, YWHAG, MYC, MAPK1, TAF10, CGN, YWHAE, PAK1, RAC1, RRAS2, PLCG1, WASF1, YWHAQ,
Protein Size: 986

Molekulargewicht: 111 kDa

Gen-ID: 9181

NCBI Accession: NM_001162383, NP_001155855

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling