GPR172B Antikörper (C-Term)

Produktnummer ABIN2788146

Der Kaninchen Polyklonal anti-GPR172B Antikörper (ABIN2788146) detektiert spezifisch GPR172B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd und Schwein.

Kurzübersicht für GPR172B Antikörper (C-Term) (ABIN2788146)

Target: GPR172B (G Protein-Coupled Receptor 172B (GPR172B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR172B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPR172B Antikörper

Bindungsspezifität: C-Term

Sequenz: SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GPR172B

Target: GPR172B (G Protein-Coupled Receptor 172B (GPR172B))

Andere Bezeichnung: SLC52A1

Hintergrund: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Alias Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e
Protein Size: 350

Molekulargewicht: 38 kDa

Gen-ID: 79581

NCBI Accession: NM_001253815, NP_001240744

UniProt: Q9HAB3