GPR172A Antikörper (C-Term)

Produktnummer ABIN2788146

Der Kaninchen Polyklonal anti-GPR172A Antikörper (ABIN2788146) detektiert spezifisch GPR172A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Schwein, Pferd, Meerschweinchen, Hund und Rind (Kuh).

Kurzübersicht für GPR172A Antikörper (C-Term) (ABIN2788146)

Target: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Reaktivität: Human, Maus, Ratte, Schwein, Pferd, Meerschweinchen, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR172A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPR172A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SLC52A2 Antibody - C-terminal region

Sequenz: SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59638-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GPR172A

Target: GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

Andere Bezeichnung: SLC52A2

Hintergrund:

Background Information: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.

Gene Name: solute carrier family 52 (riboflavin transporter), member 2

Alternative Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e

Protein Name: solute carrier family 52, riboflavin transporter, member 2

Molekulargewicht: 38kDa

Gen-ID: 79581

NCBI Accession: NP_001240744

UniProt: Q9HAB3

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response