Calcitonin Receptor Antikörper (C-Term)
Kurzübersicht für Calcitonin Receptor Antikörper (C-Term) (ABIN2788145)
Target
Alle Calcitonin Receptor (CALCR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- CALCR Antibody - C-terminal region
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Sequenz
- NQRWGRRPSN RSARAAAAAA EAGDIPIYIC HQELRNEPAN NQGEESAEII
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Homologie
- Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CALCR. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CALCR
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59632-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Calcitonin Receptor (CALCR)
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Andere Bezeichnung
- CALCR
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Hintergrund
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Background Information: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Gene Name: Calcitonin receptor
Alternative Symbols: CRT, CTR, CT-R, CTR1
Protein Name: Calcitonin receptor
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Molekulargewicht
- 52kDa
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Gen-ID
- 799
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NCBI Accession
- NP_001733
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UniProt
- P30988
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Pathways
- cAMP Metabolic Process
Target
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