Calcitonin Receptor Antikörper (C-Term)

Produktnummer ABIN2788145

Produktdetails anti-Calcitonin Receptor Antikörper

Target: Calcitonin Receptor (CALCR)

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calcitonin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NQRWGRRPSN RSARAAAAAA EAGDIPIYIC HQELRNEPAN NQGEESAEII

Homologie: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CALCR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CALCR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 474 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Andere Bezeichnung: CALCR (CALCR Produkte)

Hintergrund: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CRT, CTR, CTR1, CT-R
Protein Interaction Partner: GPRASP2, GPRASP1, RAMP3, RAMP1, FLNA, MBL2, CALM1, TOPBP1, TSHR, APOB, THBS1, LRP1, CALCA,
Protein Size: 474

Molekulargewicht: 52 kDa

Gen-ID: 799

NCBI Accession: NM_001742, NP_001733

UniProt: P30988

Pathways: cAMP Metabolic Process