SPR Antikörper (C-Term)

Produktnummer ABIN2788144

Dieses Anti-SPR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPR in WB. Geeignet für Human, Maus, Ratte, Hund, Pferd und Kaninchen.

Kurzübersicht für SPR Antikörper (C-Term) (ABIN2788144)

Target: SPR (Sepiapterin Reductase (SPR))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPR Antikörper

Bindungsspezifität: C-Term

Sequenz: ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD

Homologie: Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SPR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SPR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 261 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPR

Target: SPR (Sepiapterin Reductase (SPR))

Andere Bezeichnung: SPR

Hintergrund: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Alias Symbols: SDR38C1
Protein Interaction Partner: UBC, YWHAQ, MRPL53, SRPRB, SUGP1, SBDS, AHCYL1, SCO2, RAD23B, PPM1G, NDUFA2, IDH3G, CRK, ASS1, CAMK2G,
Protein Size: 261

Molekulargewicht: 28 kDa

Gen-ID: 6697

NCBI Accession: NM_003124, NP_003115

UniProt: P35270

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration