RNLS Antikörper (Middle Region)

Produktnummer ABIN2788137

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNLS in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für RNLS Antikörper (Middle Region) (ABIN2788137)

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNLS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNLS Antikörper

Bindungsspezifität: Middle Region

Sequenz: GMKIGVPWSC RYLSSHPCIC FISIDNKKRN IESSECGPSV VIQTTVPFGV

Homologie: Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rnls. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 300 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Andere Bezeichnung: Rnls

Hintergrund: Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Alias Symbols: 6530404N21Rik, AI452315, AW060440, C10orf59
Protein Size: 300

Molekulargewicht: 33 kDa

Gen-ID: 67795

NCBI Accession: NM_001167818, NP_001161290

UniProt: A7RDN6