GRM7 Antikörper (C-Term)

Produktnummer ABIN2788134

Dieses Anti-GRM7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRM7 in WB. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für GRM7 Antikörper (C-Term) (ABIN2788134)

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRM7 Antikörper

Bindungsspezifität: C-Term

Sequenz: HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GRM7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GRM7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 915 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRM7

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Andere Bezeichnung: GRM7

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: UBC, PICK1, TUBA8, TUBA1B, TUBA1A, TUBA3C, GNAQ, GRIPAP1, FLNA, TUBA4A, CALM3, CALM1, PRKCA, GRIP1, SDCBP,
Protein Size: 915

Molekulargewicht: 99 kDa

Gen-ID: 2917

NCBI Accession: NM_000844, NP_000835

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour