CORT Antikörper (N-Term)

Produktnummer ABIN2788111

Dieses Anti-CORT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CORT in WB. Geeignet für Human.

Kurzübersicht für CORT Antikörper (N-Term) (ABIN2788111)

Target: CORT (Cortistatin (CORT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CORT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CORT Antikörper

Bindungsspezifität: N-Term

Sequenz: MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CORT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CORT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 155 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CORT

Target: CORT (Cortistatin (CORT))

Andere Bezeichnung: CORT

Hintergrund: This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Alias Symbols: CST-14, CST-17, CST-29
Protein Interaction Partner: MRGPRX2, GHSR, SSTR5, SSTR4, SSTR3, SSTR2, SSTR1,
Protein Size: 155

Molekulargewicht: 2 kDa

Gen-ID: 1325

NCBI Accession: NM_001302, NP_001293

UniProt: O00230