Synaptotagmin V Antikörper (Middle Region)
Kurzübersicht für Synaptotagmin V Antikörper (Middle Region) (ABIN2788086)
Target
Alle Synaptotagmin V (SYT5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- YLLPDKRRRY ETKVHRQTLN PHFGETFAFK VPYVELGGRV LVMAVYDFDR
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SYT5. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SYT5
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 386 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Synaptotagmin V (SYT5)
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Andere Bezeichnung
- SYT5
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Hintergrund
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Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).
Alias Symbols: -
Protein Interaction Partner: POLR2E, NRXN1, SYT3, SYT5, RAB1A,
Protein Size: 386 -
Molekulargewicht
- 43 kDa
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Gen-ID
- 6861
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NCBI Accession
- NM_003180, NP_003171
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UniProt
- O00445
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Pathways
- Synaptic Vesicle Exocytosis
Target
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