FBXL12 Antikörper (C-Term)

Produktnummer ABIN2788057

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXL12 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Schwein, Kaninchen, Rind (Kuh) und Pferd.

Kurzübersicht für FBXL12 Antikörper (C-Term) (ABIN2788057)

Target: FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Schwein, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXL12 Antikörper

Bindungsspezifität: C-Term

Sequenz: PTEILSSCLT MPKLRVLELQ GLGWEGQEAE KILCKGLPHC MVIVRACPKE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL12. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FBXL12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 326 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL12

Target: FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

Andere Bezeichnung: FBXL12

Hintergrund: Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: FLJ20188, Fbl12
Protein Interaction Partner: LNX1, DOCK8, PRAME, STYX, HSP90AA1, CUL1, SKP1, RNF32, ECSIT, MAST1, CDC37, PSEN2, PSEN1, APOE, A2M, UBC, COPS6, RBX1, CDKN1C, JUN, FXYD3, SMAD1, TGFBR1,
Protein Size: 326

Molekulargewicht: 37 kDa

Gen-ID: 54850

NCBI Accession: NM_017703, NP_060173

UniProt: Q9NXK8

Pathways: SARS-CoV-2 Protein Interaktom