USP6 Antikörper (C-Term)

Produktnummer ABIN2788027

Der Kaninchen Polyklonal anti-USP6 Antikörper (ABIN2788027) detektiert spezifisch USP6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für USP6 Antikörper (C-Term) (ABIN2788027)

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-USP6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: USP6 Antibody - C-terminal region

Sequenz: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against USP6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59335-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu USP6

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Andere Bezeichnung: USP6

Hintergrund:

Background Information: USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform  2, but not isoform  3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene Name: ubiquitin specific peptidase 6 (Tre-2 oncogene)

Alternative Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short

Protein Name: Ubiquitin carboxyl-terminal hydrolase 6

Molekulargewicht: 119kDa

Gen-ID: 9098

UniProt: P35125