USP6 Antikörper (C-Term)

Produktnummer ABIN2788027

Produktdetails anti-USP6 Antikörper

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against USP6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu USP6

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Andere Bezeichnung: USP6 (USP6 Produkte)

Hintergrund: USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Protein Interaction Partner: EXOSC8, CALM2, MDFI, APP, ATXN7L3, ANKRD44, RAB33B, MYL2, ARF6, RAC1, CDC42, UBC, USP32,
Protein Size: 1089

Molekulargewicht: 119 kDa

Gen-ID: 9098