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CDC27 Antikörper (Cell Division Cycle 27 Homolog (S. Cerevisiae)) C-Term Primary Antibody

CDC27 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788001
$389.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle CDC27 Antikörper anzeigen
    CDC27
    Bindungsspezifität
    • 17
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 67
    • 44
    • 27
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 75
    • 7
    Kaninchen
    Klonalität
    • 67
    • 15
    Polyklonal
    Konjugat
    • 34
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDC27 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 27
    • 26
    • 22
    • 14
    • 13
    • 11
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    SYIDSAVISP DTVPLGTGTS ILSKQVQNKP KTGRSLLGGP AALSPLTPSF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CDC27. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of human CDC27
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CDC27
    Andere Bezeichnung
    CDC27 (CDC27 Produkte)
    Synonyme
    ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2, wu:fb54g06, wu:fc88c12, AI452358, BC023187, CDC27, NV10210, cell division cycle 27, cell division cycle 27 S homeolog, cell division cycle protein 27 homolog, anaphase-promoting complex subunit Apc3, CDC27, cdc27, Cdc27, cdc27.S, LOC100123129, nuc2
    Hintergrund
    The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y.
    Alias Symbols: APC3, HNUC, NUC2, H-NUC, ANAPC3, CDC27Hs, D0S1430E, D17S978E
    Protein Size: 343
    Molekulargewicht
    37 kDa
    Gen-ID
    996
    NCBI Accession
    NM_001114091, NP_001107563
    UniProt
    P30260
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