RECK Antikörper (Middle Region)

Produktnummer ABIN2787984

Produktdetails anti-RECK Antikörper

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RECK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Reck. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 971 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RECK

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Andere Bezeichnung: Reck (RECK Produkte)

Synonyme: ST15 antikoerper, St15 antikoerper, mRECK antikoerper, reversion inducing cysteine rich protein with kazal motifs antikoerper, reversion-inducing-cysteine-rich protein with kazal motifs antikoerper, RECK antikoerper, Reck antikoerper

Hintergrund: Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971

Molekulargewicht: 104 kDa

Gen-ID: 53614

NCBI Accession: NM_016678, NP_057887

UniProt: Q9Z0J1