RECK Antikörper (Middle Region)
Kurzübersicht für RECK Antikörper (Middle Region) (ABIN2787984)
Target
Alle RECK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Reck. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 971 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Andere Bezeichnung
- Reck
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Hintergrund
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Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 -
Molekulargewicht
- 104 kDa
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Gen-ID
- 53614
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NCBI Accession
- NM_016678, NP_057887
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UniProt
- Q9Z0J1
Target
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