alpha 2 Antiplasmin Antikörper (N-Term)
Kurzübersicht für alpha 2 Antiplasmin Antikörper (N-Term) (ABIN2787972)
Target
Alle alpha 2 Antiplasmin (SERPINF2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- CSRDPTPEQT HRLARAMMAF TADLFSLVAQ TSTCPNLILS PLSVALALSH
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Homologie
- Cow: 91%, Horse: 100%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SERPINF2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SERPINF2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 491 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
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Andere Bezeichnung
- SERPINF2
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Hintergrund
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This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: A2AP, AAP, ALPHA-2-PI, API, PLI
Protein Interaction Partner: FN1, BCAP31, SSR1, UBC, CANX, SERPINB12, F11, KLK13, KLK6, PRSS1, SERPINF2, PLAU, TGM2, PLG, KLK2, FGA, F13A1, CFD, ELANE, DEFA1, CTRB1,
Protein Size: 491 -
Molekulargewicht
- 54 kDa
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Gen-ID
- 5345
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NCBI Accession
- NM_000934, NP_000925
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UniProt
- P08697
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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