Interleukin 17a Antikörper (N-Term)

Produktnummer ABIN2787948

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Interleukin 17a in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Rind (Kuh), Schwein, Hund, Ziege, Pferd und Kaninchen.

Kurzübersicht für Interleukin 17a Antikörper (N-Term) (ABIN2787948)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Human, Ratte, Rind (Kuh), Schwein, Hund, Ziege, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Interleukin 17a Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IL17A Antibody - N-terminal region

Sequenz: MTPGKTSLVS LLLLLSLEAI VKAGITIPRN PGCPNSEDKN FPRTVMVNLN

Homologie: Cow: 83%, Dog: 85%, Goat: 83%, Horse: 77%, Human: 100%, Pig: 83%, Rabbit: 92%, Rat: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against IL17A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59132-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL17A

Hintergrund:

Background Information: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Gene Name: Interleukin 17A

Alternative Symbols: IL17, CTLA8, IL-17, CTLA-8, IL-17A

Protein Name: Interleukin-17A

Molekulargewicht: 15kDa

Gen-ID: 3605

NCBI Accession: NP_002181

UniProt: Q16552